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Gene : AT4G02940 A. thaliana

DB identifier  ? AT4G02940 Secondary Identifier  ? locus:2139345
Brief Description  oxidoreductase, 2OG-Fe(II) oxygenase family protein
TAIR Computational Description  oxidoreductase, 2OG-Fe(II) oxygenase family protein;(source:Araport11)
TAIR Curator Summary  ALKBH10B is a functional RNA N6-methyladenosine demethylase. Reduction in ALKBH10B decreases m6A levels, and affects the stability of flowering time genes including FT, SPL3 and SPL9. Mutant plants are early flowering.
TAIR Short Description  oxidoreductase, 2OG-Fe(II) oxygenase family protein
TAIR Aliases  ALKBH10B

1 Gene Rifs

1 Organism

9 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 4726  
Location: Chr4:1306313-1311038

Gene models - AT4G02940 AT4G02940

? Gene models

Transcripts: 1  Exons: 7  Introns: 6 

Overlapping Features

? Genome features that overlap coordinates of this Gene

8 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
AK10B_ARATH function Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:29180595). ALKBH10B-mediated mRNA m6A demethylation stabilizes the mRNA of the key flowering time regulators FT, SPL3 and SPL9, which are involved in the control of floral transition (PubMed:29180595).
AK10B_ARATH similarity Belongs to the alkB family.

1 Proteins

Function

Gene Ontology

cellular component
No terms in this category.
molecular function
mRNA binding  ? ECO  
demethylase activity  ? ECO  
mRNA N6-methyladenosine dioxygenase activity  ? ECO  
metal ion binding  ? ECO  
biological process
vegetative to reproductive phase transition of meristem  ? ECO  
mRNA catabolic process  ? ECO  

Interactions

Interaction Network

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Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets