DB identifier | AT1G29690 | Secondary Identifier | locus:2013673 |
Name | constitutively activated cell death 1 | Brief Description | MAC/Perforin domain-containing protein |
TAIR Computational Description | MAC/Perforin domain-containing protein;(source:Araport11) |
TAIR Curator Summary | Encodes a protein containing a domain with significant homology to the MACPF (membrane attack complex and perforin) domain of complements and perforin proteins that are involved in innate immunity in animals. Transgenic <i>cad1-1</i> mutant plants show lesions seen in the hypersensitive response, as well as a spontaneous activation of expression of pathogenesis-related genes and leading to a 32-fold increase in salicylic acid (SA). CAD1 is postulated to act as a negative regulator controlling SA-mediated pathway of programmed cell death in plant immunity. |
TAIR Short Description | MAC/Perforin domain-containing protein |
TAIR Aliases | CAD1, NSL2 |