|
AT1G29690
|
locus:2013673
|
CAD1
|
constitutively activated cell death 1
|
3134
 |
Chr1: 10379020-10382153 |
A. thaliana
|
MAC/Perforin domain-containing protein;(source:Araport11) |
Encodes a protein containing a domain with significant homology to the MACPF (membrane attack complex and perforin) domain of complements and perforin proteins that are involved in innate immunity in animals. Transgenic cad1-1 mutant plants show lesions seen in the hypersensitive response, as well as a spontaneous activation of expression of pathogenesis-related genes and leading to a 32-fold increase in salicylic acid (SA). CAD1 is postulated to act as a negative regulator controlling SA-mediated pathway of programmed cell death in plant immunity. |
MAC/Perforin domain-containing protein |
CAD1, NSL2 |
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