Genomics
Overlapping Features
Genome features that overlap coordinates of this Gene
CDSs: 23, Exons: 14, Five Prime UTRs: 2, mRNAs: 2, Three Prime UTRs: 2, Transposable Element: 1, Transposon Fragment: 1
Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
SUV2_ARATH-2 SUV2_ARATH | function | Required for tolerance to DNA-damaging and cross-linking agents such as UVB irradiation, gamma-radiation, aphidicolin, ionizing radiation and hydroxyurea (HU), cisplatin (CDDP) and mitomycin C (MMC) (PubMed:19619158, PubMed:19619159, PubMed:28556304). Involved in cell-cycle G2/M arrest in response to DNA damage (PubMed:19619158, PubMed:19619159). Required for aluminum-dependent gene regulation and root growth inhibition in an ATR-dependent manner by halting cell cycle progression and triggering loss of the quiescent center (QC) (PubMed:28556304). |
SUV2_ARATH-2 SUV2_ARATH | similarity | Belongs to the serpin family. |
SUV2_ARATH-2 SUV2_ARATH | tissue specificity | Accumulates throughout the root tip. |
Function
Gene Ontology
cellular component | |
---|---|
nucleus | ECO |
cytoplasm | ECO |
molecular function | |
phosphoprotein phosphatase activity | ECO |
protein dimerization activity | ECO |
biological process | |
response to hydroxyurea | ECO |
regulation of cell cycle | ECO |
response to gamma radiation | ECO |
positive regulation of cell cycle G2/M phase transition | ECO |
response to ionizing radiation | ECO |
response to cisplatin | ECO |
DNA damage response | ECO |
response to UV-B | ECO |
response to aluminum ion | ECO |
Interactions
Interaction Network
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