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Gene : APG5 A. thaliana

DB identifier  ? AT5G17290 Secondary Identifier  ? locus:2167195
Name  ? AUTOPHAGY 5 Brief Description  autophagy protein Apg5 family
TAIR Computational Description  autophagy protein Apg5 family;(source:Araport11)
TAIR Curator Summary  Autophagy protein ATG5. Forms a conjugate with ATG12 with an essential role in plant nutrient recycling. Mutants missing ATG5 display early senescence and are hypersensitive to nitrogen or carbon starvation, accompanied by a more rapid loss of organellar and cytoplasmic proteins.
TAIR Short Description  autophagy protein Apg5 family
TAIR Aliases  APG5, ATATG5, ATG5

4 Gene Rifs

1 Organism

38 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 3813  
Location: Chr5:5686135-5689947 reverse strand

Gene models - APG5 AT5G17290

? Gene models

Transcripts: 1  Exons: 8  Introns: 7 

Overlapping Features

? Genome features that overlap coordinates of this Gene

9 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
ATG5_ARATH function Required for autophagy. Conjugation to ATG12 is essential for plant nutrient recycling (PubMed:16040659). Involved in a negative feedback loop that modulates NPR1-dependent salicylic acid (SA) signaling and limits senescence and immunity-related programmed cell death (PCD) in plants (PubMed:19773385). Involved in complete proteolysis of chloroplast stroma proteins in senescent leaves (PubMed:23327451). Involved in the degradation of damaged peroxisomes (PubMed:24463818).
ATG5_ARATH similarity Belongs to the ATG5 family.
ATG5_ARATH tissue specificity Ubiquitous.

1 Proteins

Function

Gene Ontology

cellular component
Atg12-Atg5-Atg16 complex  ? ECO  
phagophore assembly site membrane  ? ECO  
molecular function
No terms in this category.
biological process
autophagy  ? ECO  
C-terminal protein lipidation  ? ECO  
defense response to fungus  ? ECO  
protein transport  ? ECO  
leaf senescence  ? ECO  
autophagy of mitochondrion  ? ECO  
response to starvation  ? ECO  
cellular response to nitrogen starvation  ? ECO  
nucleophagy  ? ECO  
autophagosome assembly  ? ECO  

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets