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Gene : SIC A. thaliana

DB identifier  ? AT4G24500 Secondary Identifier  ? locus:2121870
Name  ? SICKLE Brief Description  hydroxyproline-rich glycoprotein family protein
TAIR Computational Description  hydroxyproline-rich glycoprotein family protein;(source:Araport11)
TAIR Curator Summary  Encodes a proline-rich protein SICKLE (SIC). Required for development and abiotic stress tolerance. Involved in microRNA biogenesis. It is involved in mRNA splicing. It is a single copy gene in Arabidopsis and likely specific to higher plants. Along with RCN1, it functions in regulating auxin transport processes in part by regulating the recycling of PIN1 and PIN2 auxin transporters. It is required for circadian clock temperature responses.
TAIR Short Description  hydroxyproline-rich glycoprotein family protein
TAIR Aliases  RON3, SIC, WARP2

2 Gene Rifs

1 Organism

8 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 2235  
Location: Chr4:12658433-12660667

Gene models - SIC AT4G24500

? Gene models

Transcripts: 3  Exons: 10  Introns: 7 

Overlapping Features

? Genome features that overlap coordinates of this Gene

12 Child Features

1 Cross References

1 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
SIC_ARATH-2 SIC_ARATH developmental stage Localized in the shoot apical meristem (SAM) dome, the emerging leaf and root primordia, the provascular strands of developing seedlings, and the epidermis and cortex of the meristematic and elongation zones of the primary root tip, and in the protoderm of heart- and torpedo- stage embryos.
SIC_ARATH-2 SIC_ARATH function Involved in miRNAs and siRNAs biogenesis and thus promotes gene silencing (PubMed:23071326). Modulates auxin (IAA) transport-related developmental programs by regulating protein phosphatase 2A (PP2As)-driven auxin efflux carrier PIN proteins recycling and polarity (PubMed:26888284). Required during development (PubMed:23071326, PubMed:26888284). Necessary for abiotic stress (e.g. chilling and salt) tolerance (PubMed:23071326).
SIC_ARATH-2 SIC_ARATH subcellular location Colocalizes with miRNA biogenesis components in distinct subnuclear bodies (PubMed:23071326). Localized in the nuclei, excluding the nucleolus, in all cells of the root apical meristem. In young cortical cells of the root, localized in the nucleus and cytosol (PubMed:26888284).
SIC_ARATH-2 SIC_ARATH tissue specificity Expressed in the shoot apical meristem (SAM), embryos, seedlings, root tips, and root and leaf primordia.

3 Proteins

Function

Gene Ontology Displayer

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets