Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
MBD4L_ARATH-5 MBD4L_ARATH-2 MBD4L_ARATH MBD4L_ARATH-4 MBD4L_ARATH-3 | function | Monofunctional DNA glycosylase targeting U:G and T:G mispairs (PubMed:23994068). Excises uracil derivatives and exhibits a preference for a CpG sequence context, irrespective of the methylation status of the complementary strand (PubMed:23994068). The activity follows a biphasic kinetics, with an initial burst of product accumulation followed by a slower phase (PubMed:23994068). Specifically binds its reaction product (PubMed:23994068). Triggers the base excision repair (BER) pathway (PubMed:25900572). |
MBD4L_ARATH-5 MBD4L_ARATH-2 MBD4L_ARATH MBD4L_ARATH-4 MBD4L_ARATH-3 | tissue specificity | Isoform 1 and isoform 4: Expressed in leaves and flowers, but not in roots or stems. |
Function
Gene Ontology
cellular component | |
---|---|
nucleus | ECO |
molecular function | |
DNA binding | ECO |
hydrolase activity | ECO |
biological process | |
DNA repair | ECO |
Interactions
Interaction Network
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