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Gene : AT1G09060 A. thaliana

DB identifier  ? AT1G09060 Secondary Identifier  ? locus:2036014
Brief Description  JmjC domain protein JMJ24
TAIR Computational Description  JmjC domain protein JMJ24;(source:Araport11)
TAIR Curator Summary  JMJ24 is a nuclear localized JmjC domain containing protein. It has been shown to bind to transcribed regions AtSN1 and solo LTR and the promoter of SDC. JMJ24 appears to regulate basal levels of transcription of silenced loci in part by controlling methylation in heterochromatic regions.
TAIR Short Description  Zinc finger, RING-type;Transcription factor jumonji/aspartyl beta-hydroxylase
TAIR Aliases  JMJ24

4 Gene Rifs

1 Organism

13 Publications

0 Synonyms

Genomics

Genome feature

Region: gene ? Length: 4763  
Location: Chr1:2921064-2925826 reverse strand

Gene models - AT1G09060 AT1G09060

? Gene models

Transcripts: 4  Exons: 55  Introns: 51 

Overlapping Features

? Genome features that overlap coordinates of this Gene

22 Child Features

1 Cross References

0 Downstream Intergenic Region

0 Located Features

1 Upstream Intergenic Region

Proteins

Curated comments from UniProt

Type Comment Proteins
JMJ24_ARATH JMJ24_ARATH-2 function Binds histone H3 but seems to have lost demethylase activity probably due to its inability to bind iron Fe(2+) (PubMed:26979329). Possesses E3 ubiquitin ligase activity and targets directly CMT3 for proteasomal degradation to initiate destabilization of the heterochromatic state (e.g. CHG cytosine methylation and H3K9me2) of endogenous silenced loci (PubMed:26798133, PubMed:26979329). Required for the removal of repressive H3K9me2 histone marks to facilitate the transcription of AtSN1, AtMu1c, solo LTR and SDC, thus counteracting their transcriptional silencing (PubMed:26119694, PubMed:26979329). Mainly required to promote the basal level transcription of silenced loci such as TE and repeats targeted by RNA-dependent DNA methylation (RdDM) for silencing, a specialized branch of the RNA interference (RNAi) pathway (PubMed:26119694, PubMed:26979329, PubMed:28400174). Cooperates also with RNAi pathways for gene silencing both by contributing to the production of 24-nt siRNA to initiate RdDM and by recruiting RDR2 to enable local transcripts to make dsRNA (PubMed:26119694, PubMed:28400174). Antagonizes histone H3K9 demethylase IBM1/JMJ25 function (PubMed:28400174).
JMJ24_ARATH JMJ24_ARATH-2 similarity Belongs to the JARID1 histone demethylase family.
JMJ24_ARATH JMJ24_ARATH-2 tissue specificity Expressed in inflorescences, flowers, roots, siliques, leaves and stems, especially in the vasculature (mainly phloem), with highest levels in floral organs.

2 Proteins

Function

Interactions

Interaction Network

Expression

eFP Visualization

Data Source: BAR




Co-expression

Querying ATTED Service...
Data Source: ATTED-II
Top N
LS: LS is a monotonic transformation (negative logit) of MR index. Larger LS indicates stronger co-expression.

 

Homology

Phytozome Homologs

Data Source: Phytozome


0 Homologues

 

Other

9 Data Sets