Genomics
Genome feature
| Region: |
gene
|
Length: |
5809
 |
| Location: | Chr1:20840091-20845899 reverse strand | ||
Overlapping Features Displayer
Proteins
Curated comments from UniProt
| Type | Comment | Proteins |
|---|---|---|
| TFB1A_ARATH | function | Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. |
| TFB1A_ARATH A0A1P8AST3_ARATH A0A1P8ASX6_ARATH | similarity | Belongs to the TFB1 family. |
Function
Gene Ontology
| cellular component | |
|---|---|
|
transcription factor TFIIH core complex
|
ECO |
| molecular function | |
| No terms in this category. | |
| biological process | |
|
nucleotide-excision repair
|
ECO |
|
DNA-templated transcription
|
ECO |
Interactions
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