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GO Term : GO:0036503 ERAD pathway GO

Namespace  biological_process Obsolete  false
Description  The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.

0 Cross References

2 Data Sets

1 Ontology

72 Ontology Annotations

20 Parents

38 Relations

4 Synonyms