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GO Term : GO:0009380 excinuclease repair complex GO

Namespace  cellular_component Obsolete  false
Description  Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.

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1 Ontology

Trail: GOTerm

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8 Parents

Trail: GOTerm

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Trail: GOTerm

2 Synonyms

Trail: GOTerm