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Gene : PID A. thaliana

DB identifier  ? AT2G34650 Secondary Identifier  ? locus:2062268
Name  ? PINOID Brief Description  Protein kinase superfamily protein
TAIR Computational Description  Protein kinase superfamily protein;(source:Araport11)
TAIR Curator Summary  Encodes a protein serine/threonine kinase that may act as a positive regulator of cellular auxin efflux, as a a binary switch for PIN polarity, and as a negative regulator of auxin signaling. Recessive mutants exhibit similar phenotypes as pin-formed mutants in flowers and inflorescence but distinct phenotypes in cotyledons and leaves. Expressed in the vascular tissue proximal to root and shoot meristems, shoot apex, and embryos. Expression is induced by auxin. Overexpression of the gene results in phenotypes in the root and shoot similar to those found in auxin-insensitive mutants. The protein physically interacts with TCH3 (TOUCH3) and PID-BINDING PROTEIN 1 (PBP1), a previously uncharacterized protein containing putative EF-hand calcium-binding motifs. Acts together with ENP (ENHANCER OF PINOID) to instruct precursor cells to elaborate cotyledons in the transition stage embryo. Interacts with PDK1. PID autophosphorylation is required for the ability of PID to phosphorylate an exogenous substrate. PID activation loop is required for PDK1-dependent PID phosphorylation and requires the PIF domain. Negative regulator of root hair growth. PID kinase activity is critical for the inhibition of root hair growth and for maintaining the proper subcellular localization of PID.
TAIR Short Description  Protein kinase superfamily protein
TAIR Aliases  ABR, PID

18 Gene Rifs

1 Organism

67 Publications

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1 Downstream Intergenic Region

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1 Upstream Intergenic Region

Proteins

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1 Proteins

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