Proteins
Curated comments from UniProt
Type | Comment | Proteins |
---|---|---|
FBT1_ARATH | function | Mediates folate monoglutamate transport involved in tetrahydrofolate biosynthesis. It also mediates transport of antifolates, such as methotrexate and aminopterin. |
FBT1_ARATH A0A1P8AYE7_ARATH | similarity | Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family. |
FBT1_ARATH | subcellular location | Expressed in green as well as in non-green plastids. |
FBT1_ARATH | tissue specificity | Constitutively expressed at low level. |
Function
Gene Ontology
cellular component | |
---|---|
chloroplast envelope | ECO |
chloroplast membrane | ECO |
molecular function | |
folic acid transmembrane transporter activity | ECO |
5-formyltetrahydrofolate transmembrane transporter activity | ECO |
methotrexate transmembrane transporter activity | ECO |
biological process | |
methotrexate transport | ECO |