| Description | This entry represents the adaptive-response sensory-kinase SasA family, a member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression []. This family of proteins participate in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC []. It is required for robustness of the circadian rhythm of gene expression and involved in clock output [, ]. The kaiABC complex has a core comprising a kaiC homohexamer, a kaiB dimer and two kaiA dimers. KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it. Proteins in this entry contain a histidine kinase domain. | Name | Adaptive-response sensory-kinase SasA |
| Short Name | Kinase_SasA | Type | Family |
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