help  | faq  | software  | BAR

Protein Domain : IPR008030

Description  NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA [ ]. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. It lacks most of the active site residues of the SDR (short-chain dehydrogenases/reductases) family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG [].This domain can also be found in other atypical SDRs, such as HSCARG (an NADPH sensor) [ ] and PCBER (phenylcoumaran benzylic ether reductase) []. Name  NmrA-like domain
Short Name  NmrA-like Type  Domain
Quick Links:
 
Quick Links:
 

4 Publications

Genomics

1 Cross References

 

Other

1 Child Features

1 Data Sets

0 Parent Features

41 Protein Domain Regions