Description | This domain is the substrate binding domain of shikimate dehydrogenase [ ]. Shikimate dehydrogenase catalyses the fourth step of the mycobacterial Shikimate pathway, which results in the biosynthesis of chorismate. Chorismate is a precursor of aromatic amino acids, naphthoquinones, menaquinones and mycobactins [, ]. This pathway is an important target for antibacterial agents, especially against Mycobacterium tuberculosis, since it does not occur in mammals. | Name | Shikimate dehydrogenase substrate binding, N-terminal |
Short Name | Shikimate_DH-bd_N | Type | Domain |