Description | The N-terminal dimerisation domain of the transcriptional activator hepatocyte nuclear factor 1 is essential for DNA binding and association of the transcriptional coactivator, DCoH (dimerization cofactor of HNF-1). This domain forms a unique four-helical bundle which is largely conserved when dimerisation occurs [ ]. | Name | Hepatocyte nuclear factor 1, N-terminal domain superfamily |
Short Name | HNF1_dimer_N_dom_sf | Type | Homologous_superfamily |