| Description | Pheromone alpha factor receptor (STE2) is the receptor for the peptide pheromone alpha factor, which is a mating factor of yeast [ ]. Saccharomyces cerevisiae haploid cells secrete and respond to peptide mating factors; alpha cells secrete alpha factor, which induces cell-cycle arrest and expression of various genes in a cells, while a cells produce a factor, which has similar actions on alpha cells.This superfamily represents a double transmembrane domain towards the N terminus of the alpha factor receptor. The ligand-binding site is probably in this domain [ ]. | Name | Pheromone alpha factor receptor, double transmembrane domain superfamily |
| Short Name | STE2_TM1-TM2_sf | Type | Homologous_superfamily |
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