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Protein Domain : IPR015405

Description  This entry represents a domain found at the C-terminal end of various NADH dehydrogenases from bacteria and eukaryotes, including NADH-quinone oxidoreductase subunit G from Rickettsia typhi (NuoG) and NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial from humans (NDUFS1, also known as Complex I-75kD, CI-75kD).NuoG shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.NDUFS1 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyses electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor [ , ]. This protein is associated with mitochondrial disorders leading to a group of highly heterogeneous conditions ranging from lethal neonatal disease to adult-onset neurodegenerative disorders [, ]. Name  NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial-like
Short Name  NDUFS1-like_C Type  Domain
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3 Publications

Genomics

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1 Data Sets

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9 Protein Domain Regions