Description | The 2-oxoglutarate dehydrogenase (OGDH) multienzyme complex is rate-limiting in the TCA cycle in many species, and is an essential nexus in the utilization of sugar and amino acids, funnelled via 2-oxoglutarate and oxidized to succinyl-CoA, process which releases CO2 and results in the reduction of NAD to NADH [ ]. An alternative name for this complex is alpha-ketoglutarate dehydrogenase (KGD).This superfamily represents the C terminus of the multifunctional 2-oxoglutarate metabolism enzyme KGD [ ]. | Name | Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily |
Short Name | KGD_C_sf | Type | Homologous_superfamily |