Description | Glucose-6-phosphate dehydrogenase (G6PD) [ ] catalyses the first step in the pentose pathway, the reduction of glucose-6-phosphate to gluconolactone 6-phosphate. A lysine residue has been identified as a reactive nucleophile associated with the activity of the enzyme []. The sequence around this lysine is totally conserved from bacterial to mammalian G6PD's and is used as the pattern to identify the proteins associated with this entry. | Name | Glucose-6-phosphate dehydrogenase, active site |
Short Name | G6P_DH_AS | Type | Active_site |