| Description | This superfamily represents the domain 2 found in phosphate acetyltransferase.Phosphotransacetylase ( ) catalyses reversible transfer of the acetyl group from acetyl phosphate to coenzyme A (CoA), forming acetyl-CoA and inorganic phosphate [ , ].The Phosphotransacetylase enzyme is composed of six monomers per asymmetric unit. Each monomer has an α/β structure and consists of two domains (I and II). Domain I forms an α-β-α structure, with a strictly parallel five-stranded β-sheet in the middle 'sandwiched' by α-helices on each side. It contains the N- and C-terminal segments, a lactate dehydrogenase (LDH)-like nucleotide-binding fold (Rossmann fold), and a helical subdomain consisting of four α-helices. Domain II also adopts a typical α-β-α sandwich structure with a mixed six-stranded β-sheet that is embraced by three helices on one side and two helices on the other side. The two domains are separated by a distinct cleft []. | Name | Phosphate acetyltransferase, domain 2 |
| Short Name | P_AcTrfase_dom2 | Type | Homologous_superfamily |
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