Description | This entry describes the coenzyme PQQ (pyrrolo-quinoline-quinone) biosynthesis protein PqqC and its related protein, CADD. Pyrroloquinoline quinone (PQQ) is the prosthetic group of several bacterial enzymes, including methanol dehydrogenase of methylotrophs and the glucose dehydrogenase of a number of bacteria [ ]. PQQC is an oxidase whose reaction involves a ring closure and eight-electron oxidation of its substrate (AHQQ) to produce PQQ [].Chlamidia specific toxin CADD, also known as PqqC-like protein, which induces apoptosis in mammalian cell lines [ ]. BesC from Streptomyces cattleya, shows homology to CADD, has been shown to catalyse formation of 4-Cl-allylglycine from 4-Cl-lysine and requires Fe(II) as a cofactor []. | Name | Pyrroloquinoline-quinone synthase-like |
Short Name | PqqC-like | Type | Family |