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Protein Domain : IPR019581

Description  The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis [ ]. This close association with crucial RNA sequences, together with extensive genetic evidence, suggests that Prp8 could directly affect the function of the catalytic core, perhaps acting as a splicing cofactor []. Name  Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding
Short Name  Prp8_U5-snRNA-bd Type  Domain
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9 Protein Domain Regions