Description | The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis [ ]. This close association with crucial RNA sequences, together with extensive genetic evidence, suggests that Prp8 could directly affect the function of the catalytic core, perhaps acting as a splicing cofactor []. | Name | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding |
Short Name | Prp8_U5-snRNA-bd | Type | Domain |