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Protein Domain : IPR044691

Description  This entry includes DCC1 (thioredoxin DXXCXXC motif-containing protein 1, AT5G50100) from Arabidopsis thaliana [ ], which belongs to the thiol-disulfide oxidoreductase family. Members of this family contain a conserved DxxCxxC motif in their N-terminal. Two Cys residues present in this motif determined the function of these proteins as Thioredoxins (Trxs), key enzymes for modulating ROS scavenging through the reduction of specific S-S groups. DCC1 is localised in mitochondria and directly interacts with CARBONIC ANHYDRASE2 (CA2), an essential subunit of the respiratory chain NADH dehydrogenase complex (Complex I). DCC1 catalyses a redox modification on CA2, resulting in the regulation of Complex I activity and ROS homeostasis which is important for de novo shoot initiation and improvement the capacity of plant regeneration [].This entry also includes uncharacterised proteins from bacteria. Name  Thioredoxin DCC1
Short Name  DCC1_Trx Type  Family
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