| Description | This entry represents the C-terminal domain of Isocitrate dehydrogenase [NADP] from Rickettsia typhi and similar bacterial proteins. It is also found in the hypothetical protein TT1725 from Thermus thermophilus HB8. The sequence is conserved in three predicted prokaryotic proteins with unknown functions, including Deinococcus radiodurans, Stigmatella aurantiaca, and Mycobacterium leprae. The presence of positively-charged residues in the α1 helix suggests this region binds to a protein with a negatively charged region or to nucleic acids []. | Name | Isocitrate dehydrogenase/Hypothetical protein TT1725, C-terminal domain superfamily |
| Short Name | Isocitrate_DH_TT1725_C_sf | Type | Homologous_superfamily |
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