| Description | Alpha-Ketoglutaric Semialdehyde (KGSA) Dehydrogenase (KGSADH, ) catalyses the NAD(P)-dependent conversion of KGSA to alpha-ketoglutarate. This entry includes KGSADH-II (D-glucarate/D-galactarate-inducible) and KGSADH-III (hydroxy-L-proline-inducible) from Azospirillum brasilense. Both show similar high substrate specificity for KGSA and different coenzyme specificity; KGSADH-II is NAD-dependent and KGSADH-III is NADP-dependent [ ]. This entry also includes the NADP(+)-dependent aldehyde dehydrogenase from Vibrio harveyi which catalyses the oxidation of long-chain aliphatic aldehydes to acids [, ]. | Name | Alpha-ketoglutaric semialdehyde dehydrogenase |
| Short Name | ALDH_KGSADH | Type | Family |
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