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Protein Domain : IPR036625

Description  A small domain of the E2 subunit of 2-oxo-acid dehydrogenases that is responsible for the binding of the E3 subunit. Proteins containing this domain include the branched-chain alpha-keto acid dehydrogenase complex of bacteria, which catalyses the overall conversion of alpha-keto acids to acyl-CoA and carbon dioxide; and the E3 binding protein of eukaryotic pyruvate dehydrogenase [ ].The structure of the E3-binding domain has three helices with a close bundle fold and right-handed twist going up-and-down [ ]. This structure arrangement is also found at the C-terminal of Nucleoid-associated protein Lsr2 and Protein Ku, in which it is a DNA-binding domain []. Name  E3-binding domain superfamily
Short Name  E3-bd_dom_sf Type  Homologous_superfamily
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3 Publications

Genomics

2 Cross References

 

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0 Child Features

1 Data Sets

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42 Protein Domain Regions