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Protein Domain : IPR030664

Description  Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [ ]. Succinate dehydrogenase (Sdh), a primary respiratory dehydrogenase, catalyses electron transfer from succinate to membrane-bound quinone. Fumarate reductase (Frd) catalyses the opposite reaction.The enzyme complex consists at least of four subunits. The hydrophilic catalytic domain consists of a flavoprotein that contains covalently bound FAD and an active site of the enzyme [ , ].Adenylylsulphate (APS) reductase catalyses reversibly the two-electron reduction of APS to sulphite and AMP during dissimilatory sulphate reduction or sulphur oxidation. Found in several bacterial lineages and in Archaeoglobales, APS reductase is a heterodimer composed of an alpha subunit containing a noncovalently bound FAD, and a beta subunit containing two [4Fe-4S] clusters. The alpha subunit of APS reductase shares a common evolutionary origin with fumarate reductase/succinate dehydrogenase flavoproteins []. Name  FAD-dependent oxidoreductase SdhA/FrdA/AprA
Short Name  SdhA/FrdA/AprA Type  Family
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4 Publications

Genomics

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3 Child Features

1 Data Sets

0 Parent Features

4 Protein Domain Regions