Description | This entry represents the MDR (medium-chain dehydrogenase/reductase) family.The MDR/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH [ ]. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR) []. The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a β-α form and an N-terminal catalytic domain with distant homology to GroES []. | Name | Medium-chain dehydrogenase/reductase |
Short Name | MDR_fam | Type | Family |