Description | This entry represents UDP-N-acetyl-D-mannosamine dehydrogenase wecC (also known as RffD) from Enterobacteriaceae. WecC is involved in the Enterobacterial common antigen (ECA) biosynthesis, which is part of bacterial outer membrane biogenesis [ ]. ECA is a specific surface antigen (polysaccharide) shared by all members of the Enterobacteriaceae and is restricted to this family []. It catalyses the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD+ and releasing UDP-N-acetylmannosaminuronic acid []. | Name | UDP-N-acetyl-D-mannosamine dehydrogenase WecC |
Short Name | WecC | Type | Family |