Description | The vicinal oxygen chelate (VOC) family of enzymes catalyzes a highly diverse set of chemistries that derives from one common mechanistic trait: bidentate coordination to a divalent metal centre by a substrate or intermediate or transition state through vicinal oxygen atoms. The array of reactions catalyzed by this family is mediated structurally by a common fold and protein-chelating residues that secure and localize a metal ion. The common fold has topological symmetry being comprised of two β-α-β-β-β units that form an incompletely closed barrel of β-sheet about the metal ion [ ]. | Name | Vicinal oxygen chelate (VOC) domain |
Short Name | VOC | Type | Domain |