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Protein Domain : IPR016040

Description  This entry represents NAD- and NADP-binding domains with a core Rossmann-type fold, which consists of 3-layers α/β/α, where the six β-strands are parallel in the order 321456. Many different enzymes contain an NAD/NADP-binding domain, including:C-terminal domain of alcohol dehydrogenases [ ] Tyrosine-dependent oxidoreductases (also known as short-chain dehydrogenases) [ ] N-terminal domain of glyceraldehyde-3-phosphate dehydrogenase [ ] NAD-binding domain of formate/glycerate dehydrogenases [ ] N-terminal domain of sirohaem synthase [ ] N-terminal domain of lactate dehydrogenase [ ] N-terminal domain of 6-phosphogluconate dehydrogenase (the β-sheet is extended to 8 strands) [ ] C-terminal domain of amino acid dehydrogenases (an extra N-terminal helix displaces the C-terminal helix [ ] NAD-binding domain of certain potassium channels [ ] C-terminal domain of the transcriptional repressor Rex [ ] Ornithine cyclodeaminase [ ] CoA-binding N-terminal domain of the alpha chain of succinyl-CoA synthetase [ ] Name  NAD(P)-binding domain
Short Name  NAD(P)-bd_dom Type  Domain
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12 Publications

Genomics

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1 Data Sets

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138 Protein Domain Regions