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Protein : EME1A_ARATH A. thaliana

Primary Accession  ? Q84M98 Organism . Name  Arabidopsis thaliana
Length  546   MD5 Checksum  c8f0b45d415da4de3c59dbab6a875f0a
UniProt Accession  Q84M98 Is UniProt Canonical  true
UniProt Name  EME1A_ARATH Is Fragment  false
Molecular Weight  61239.0 Name  Crossover junction endonuclease EME1A
Secondary Identifier  Q84M98

3 Comments

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1 Genes

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1 Organism

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4 Publications

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Genomics

4 Cross References

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1 Genes

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Proteins

Curated comments from UniProt

Type Comment
function Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells. Mediates a subset of meiotic recombination events that are insensitive to crossover interference.
similarity Belongs to the EME1/MMS4 family.

12 Features

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1 Isoforms

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17 Keywords

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5 Protein Domain Regions

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1 Sequence

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Other

0 Canonical Protein

0 Components

2 Data Sets

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1 Ec Numbers

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0 Locations