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Protein : MBD4L_ARATH-4 A. thaliana

Primary Accession  ? Q0IGK1-4 Organism . Name  Arabidopsis thaliana
Length  329   MD5 Checksum  04259b117d7afdb573130f24b6a8ab13
UniProt Accession  Q0IGK1 Is UniProt Canonical  false
UniProt Name  MBD4L_ARATH Is Fragment  false
Name  Methyl-CpG-binding domain protein 4-like protein Secondary Identifier  Q0IGK1-4

5 Comments

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1 Genes

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1 Organism

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5 Publications

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Genomics

10 Cross References

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1 Genes

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Proteins

Curated comments from UniProt

Type Comment
function Monofunctional DNA glycosylase targeting U:G and T:G mispairs (PubMed:23994068). Excises uracil derivatives and exhibits a preference for a CpG sequence context, irrespective of the methylation status of the complementary strand (PubMed:23994068). The activity follows a biphasic kinetics, with an initial burst of product accumulation followed by a slower phase (PubMed:23994068). Specifically binds its reaction product (PubMed:23994068). Triggers the base excision repair (BER) pathway (PubMed:25900572).
tissue specificity Isoform 1 and isoform 4: Expressed in leaves and flowers, but not in roots or stems.

0 Features

0 Isoforms

6 Keywords

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0 Protein Domain Regions

1 Sequence

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Other

1 Canonical Protein

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0 Components

2 Data Sets

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0 Ec Numbers

0 Locations