Description | Pyruvate dehydrogenase multienzyme complex (PDC) catalyzes the oxidative decarboxylation of pyruvate and the subsequent acetylation of coenzyme A to acetyl-CoA. The E1 component of PDC catalyzes the first step of the multistep process, using thiamine pyrophosphate (TPP) and a divalent cation as cofactors. E. coli PDC is a homodimeric enzyme [ ]. | Name | Pyruvate dehydrogenase E1 component, N-terminal |
Short Name | PDC_E1_N | Type | Domain |