| Description | Malate dehydrogenase (MDH) is one of the key enzymes in the citric acid cycle, facilitating both the conversion of malate to oxaloacetate and replenishing levels of oxalacetate by reductive carboxylation of pyruvate [ ]. There are several isoforms of MDH, differing in their subcellular localization and their specificity for the cofactor NAD or NADP []. Members of this family are eukaryotic NAD-dependent MDHs localized to the cytoplasm and cytosol.The enzyme from pig has been studied by X-ray crystallography [ ]. | Name | Malate dehydrogenase, NAD-dependent, cytosolic |
| Short Name | Malate_DH_NAD-dep_euk | Type | Family |
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