| Description | This family contains succinate dehydrogenase (also known as succinate:quinone oxidoreductase, SQR) subunit C of Bacillus subtilis, designated cytochrome b-558, and related sequences that include a fumarate reductase subunit C. This family is only weakly similar to the main group of succinate dehydrogenase cytochrome b subunits described by , so that some members score above the gathering threshold and some do not [ ].SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis SQR reduces low potential quinones such as menaquinone [ ]. SQR is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Members of this entry are classified as Type B as they contain one transmembrane subunit and two heme groups []. The heme and quinone binding sites reside on the cytochrome b558 subunit [, ]. The structural arrangement allows efficient electron transfer between the catalytic subunit, through iron-sulfur centres, and the transmembrane subunit containing the electron acceptor (quinone). The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes [, , , ]. | Name | Succinate dehydrogenase cytochrome b558 subunit, Firmicute |
| Short Name | Succ_DH_cyt_b558_Firmicute | Type | Family |
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