| Description | Mannitol dehydrogenases catalyse the NAD-dependent reduction of mannitol-1-phosphates as part of the phosphoenolpyruvate-dependent phosphotransferase system (PTS). The PTS facilitates the vectorial translocation of metabolisable carbohydrates to form the corresponding sugar phosphates, which are then converted to glycolytic intermediates []. Mannitol 2-dehydrogenase catalyses the NAD-dependent reduction of mannitol to fructose [].Several dehydrogenases have been shown [ ] to be evolutionary related, including mannitol-1-phosphate 5-dehydrogenase () (gene mtlD), mannitol 2-dehydrogenase ( ) (gene mtlK); mannonate oxidoreductase ( ) (fructuronate reductase) (gene uxuB); Escherichia coli hypothetical proteins ydfI and yeiQ; and yeast hypothetical protein YEL070w. | Name | Mannitol dehydrogenase |
| Short Name | Mannitol_DH | Type | Family |
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