DB identifier
|
AT1G21970 | Secondary Identifier
|
locus:2201163 |
| Name
|
LEAFY COTYLEDON 1 | Brief Description | Histone superfamily protein |
| TAIR Computational Description | Histone superfamily protein;(source:Araport11) |
| TAIR Curator Summary | Transcriptional activator of genes required for both embryo maturation and cellular differentiation. Sequence is similar to HAP3 subunit of the CCAAT-box binding factor. HAP3 subunit is divided into three domains: an amino-terminal A domain, a central B domain, and a carboxyl-terminal C domain. LEC1 shared high similarity with other HAP3 homologs only in central, B domain. LEC1 is required for the specification of cotyledon identity and the completion of embryo maturation. It was sufficient to induce embryogenic programs in vegetative cells, suggesting that LEC1 is a major embryonic regulator that mediates the switch between embryo and vegetative development. Mutants are desiccation intolerant, have trichomes on cotyledons and exhibit precocious meristem activation. Levels of the ABI3 and FUS3 transcripts were significantly reduced in developing siliques of the lec1-1 mutants, indicating that LEC1 down-regulates FUS3 and ABI3.When LEC1 is overexpressed from an inducible promoter, the expression of numerous genes involved in fatty acid biosynthesis is increased suggesting a role in positive regulation of FA biosynthesis. LEC is required for FLC activation in embryos following vernalization. |
| TAIR Short Description | Histone superfamily protein |
| TAIR Aliases | AtLEC1, EMB 212, EMB212, LEC1, NF-YB9 |
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