| Description | BCL9 is associated with B-cell acute lymphoblastic leukemia [ ]. This entry includes BCL9 and BCL9L. They are tissue-specific transcriptional cofactors that cooperate with beta-catenin. In the nucleus, Bcl9 and Bcl9l simultaneously bind beta-catenin and the transcriptional activator Pygo2 to promote the transcription of a subset of Wnt target genes. They may also have a cytoplasmic role []. | Name | B Cell Lymphoma 9 |
| Short Name | Bcl-9/Bcl-9l | Type | Family |
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