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Protein Domain : IPR019355

Description  This entry represents the cell cycle regulator Mat89b (also known as protein asunder), which plays an evolutionarily conserved role as a crucial regulator of both cell cycle and development [ , ]. It is a component of INT (Integrator) complex, being involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1 and U5 []. Mat89Bb is also required for the correct dynein-dynactin perinuclear localization []. Mat89Bb is a PNG kinase substrate that is essential for S-M cycles of early Drosophila embryogenesis, Xenopus embryonic cell cycles and morphogenesis, and cell division in cultured mammalian cells. Name  Cell cycle regulator Mat89Bb
Short Name  Cell_cycle_regulator_Mat89Bb Type  Family
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4 Publications

Genomics

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