help  | faq  | software  | BAR

Protein Domain : IPR009619

Description  CrgA is a transmembrane (TM) protein, first described in Streptomyces as being required for sporulation through the coordination of several aspects of reproductive growth. In Mycobacterium tuberculosis, CrgA is a central component of the divisome, and consists of 93 residues with two predicted TM helices (TM1: residues 29-51 and TM2: residues 66-88). CrgA facilitates the recruitment of the proteins essential for peptidoglycan synthesis to the divisome and also stabilizes the divisome. Reduced production of CrgA results in elongated cells and reduced growth rate, and loss of CrgA impairs peptidoglycan synthesis. CrgA has homologs in other actinomycetes [ ]. Name  Cell division protein CrgA
Short Name  CrgA Type  Family
Quick Links:
 
Quick Links:
 

1 Publications

Genomics

2 Cross References

 

Other

0 Child Features

1 Data Sets

0 Parent Features

0 Protein Domain Regions