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Protein Domain : IPR018867

Description  The chromosomal passenger complex of Aurora B kinase, INCENP, and Survivin has essential regulatory roles at centromeres and the central spindle in mitosis. Cell division cycle-associated protein 8, also known as Borealin, is also a member of the complex. Approximately half of Aurora B in mitotic cells is complexed with INCENP, Borealin, and Survivin [ ]. Depletion of Borealin by RNA interference delays mitotic progression and results in kinetochore-spindle mis-attachments and an increase in bipolar spindles associated with ectopic asters []. Name  Cell division protein borealin
Short Name  Cell_div_borealin Type  Family
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2 Publications

Genomics

1 Cross References

 

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1 Data Sets

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