Description | This group represents glial cell line-derived neurotrophic factor (GDNF). This is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake [, ]. Defects in GDNF are a cause of congenital central hypoventilation syndrome (also known as Ondine's curse) and are also linked with Hirschsprung disease [, ]. | Name | Glial cell line-derived neurotrophic factor |
Short Name | GDNF | Type | Family |