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Protein Domain : IPR014867

Description  Members of this family include the Bacillus subtilis spore coat protein H (CotH). Assembly of CotH requires both CotE and GerE and is required for the correct assembly of both inner and outer layers of the coat. CotH appears to be a structural component of the coat being localised at the interface of the 2 coat layers [ , , ]. Furthermore, CotH has been shown to be an atypical protein kinase. CotH-dependent phosphorylation of CotB and CotG is required for the efficient germination of B. subtilis spores [].This entry also includes CotH2/3/7 from Rhizopus delemar (mucormycosis agent), which promote invasion of host epithelial cells by adhering to receptors on the host cell surface to facilitate endocytosis of the pathogen into host cells [ , ]. Name  Spore coat protein CotH/Invasin CotH2/3/7
Short Name  Spore_coat_CotH_CotH2/3/7 Type  Family
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6 Publications

Genomics

2 Cross References

 

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1 Data Sets

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