| Description | Motilin is a gastrointestinal regulatory polypeptide produced by motilin cells in the duodenal epithelium. It is released into the general circulation at about 100-min intervals during the inter-digestive state and is the most important factor in controlling the inter-digestive migrating contractions. Motilin also stimulates endogenous release of the endocrine pancreas [ ].This domain is also found in ghrelin, a growth hormone secretagogue synthesised by endocrine cells in the stomach. Ghrelin stimulates growth hormone secretagogue receptors in the pituitary. These receptors are distinct from the growth hormone-releasing hormone receptors, and thus provide a means of controlling pituitary growth hormone release by the gastrointestinal system [ ].This domain represents a peptide sequence that lies C-terminal to motilin/ghrelin ( ) on the respective precursor peptide. Its function is unknown. | Name | Motilin/ghrelin-associated peptide |
| Short Name | Motilin_assoc | Type | Domain |
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