Annotation | Study reveals that MET18 mutation caused DNA hypermethylation at more than 1000 loci, of which about 70% were overlapped with the ROS1 targeted loci, indicating a same genetic pathway. Results show that MET18 regulates active DNA demethylation by affecting the enzymatic activity of the ROS1/DME family proteins. Thus, MET18 can regulate both active DNA demethylation and DNA methylation pathways in Arabidopsis. | Organism | A. thaliana |
Gene | MET18 | PubMed Id | 27193999 |
last updated | 2018-04-21 |