| Description | The T cell receptor beta variable family is composed of proteins that form part of the antigen-specific receptors on the surface of T lymphocytes. These receptors are crucial for the immune response, recognizing peptide-major histocompatibility complexes presented by antigen presenting cells. This interaction is essential for T cell adaptive immunity against pathogens. The family includes both functional and non-functional members, with the latter resulting from altered recombination or mutations. Upon antigen recognition, these receptors initiate a cascade of intracellular signaling pathways, leading to T cell activation, growth, and differentiation. The repertoire of these receptors is generated in the thymus and shaped by selection events to create a pool of self-restricted, non-autoaggressive T cells. | Name | T cell receptor beta variable |
| Short Name | TCR_beta_variable | Type | Family |
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