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Protein Domain : IPR039778

Description  Programmed cell death protein 4 (PDCD4) binds to eukaryotic initiation factor 4A (eIF4A), inhibits translation initiation, and acts as a tumour suppressor. It contains two C-terminal MA3 domains that bind specifically to the eIF4A N-terminal domain (eIF4A-NTD) [ , , ].This entry also includes MRF1/2/3/4 from plants. They are involved in target of rapamycin (TOR)-egulated translation control, especially under energy-deficient conditions [ ]. Name  Programmed cell death protein 4
Short Name  PDCD4 Type  Family
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4 Publications

Genomics

1 Cross References

 

Other

0 Child Features

1 Data Sets

0 Parent Features

11 Protein Domain Regions